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Herbalism is a traditional medicinal or folk medicine practice based on the use of plants and plant extracts. Herbalism is also known as botanical medicine, medicinal botany(a neologism coined by Dr. K. Seshagirirao, University of Hyderabad, India), medical herbalism, herbal medicine, herbology, and phytotherapy. Sometimes the scope of herbal medicine is extended to include fungi and bee products, as well as minerals, shells and certain animal parts.

Many plants synthesize substances that are useful to the maintenance of health in humans and other animals. These include aromatic substances, most of which are phenols or their oxygen-substituted derivatives such as tannins. Many are secondary metabolites, of which at least 12,000 have been isolated — a number estimated to be less than 10% of the total. In many cases, these substances (particularly the alkaloids) serve as plant defense mechanisms against predation by microorganisms, insects, and herbivores. Many of the herbs and spices used by humans to season food yield useful medicinal compounds.

With only a few exceptions, most herbal treatments have not been tested for safety and efficacy utilizing scientific method studies or clinical trials. The scientific and medical communities state that herbal treatments may be risk the well-being or life of the patient when used in lieu of standard medical treatments.

Role of herbal medicine in human society ]People on all continents have used hundreds to thousands of indigenous plants for treatment of ailments since prehistoric times. There is evidence from the Shanidar Cave in Iraq that suggests Neanderthals living 60,000 years ago used medicinal plants. A body that was unearthed there had been buried with eight species of plants which are still widely used in ethnomedicine around the world. Medicinal plants in a Middle Paleolithic grave Shanidar IV?, Lietava J., J Ethnopharmacol. 1992 Jan;35(3):263-6., PMID 1548898

The first generally accepted use of plants as healing agents was depicted in the cave paintings discovered in the Lascaux caves in France, which have been radiocarbon-dated to between 13,000-25,000 BCE. Medicinal herbs were found in the personal effects of an "Ice man," whose body was frozen in the Swiss Alps for more than 5,300 years, which appear to have been used to treat the parasites found in his intestines. 5300 years ago, the Ice Man used natural laxatives and antibiotics, Capasso L., Lancet. 1998;352:1864, PMID 9851424.

Anthropology theorize that animals evolved a tendency to seek out bitter plant parts in response to illness. This behavior arose because bitterness is an indicator of secondary metabolites. The risk benefit ratio favored animals and protohumans that were inclined to experiment in times of sickness. Over time, and with insight, instinct, and trial-and-error, a base of knowledge would have been acquired within early tribal communities. As this knowledge base expanded over the generations, the specialized role of the herbalist emerged. The process would likely have occurred in varying manners within a wide diversity of cultures.

Indigenous healers often claim to have learned by observing that sick animals change their food preferences to nibble at bitter herbs they would normally reject{{Fact|date=July 2007-->. Field biologists have provided corroborating evidence based on observation of diverse species, such as [chimpanzees, [chickens, [sheep and [butterfly. [Lowland gorillas take 90% of their diet from the fruits of ''[Aframomum melegueta'', a relative of the [ginger plant, that is a potent antimicrobial and apparently keeps [shigellosis and similar infections at bay.''Wild Health: How Animals Keep Themselves Well and What We Can Learn From Them, '' Cindy Engel, Houghton Mifflin, 2002

]Researchers from Ohio Wesleyan University found that some birds select nesting material rich in antimicrobial agents which protect their young from harmful bacteriaJan Ichida, Proceedings of the 104th General Meeting of the American Society for Microbiology. reported in Birds use herbs to protect their nests, BJS, Science Blog, Wed, 2004-05-26.

Sick animals tend to forage plants rich in secondary metabolites, such as tannins and alkaloids{{Fact|date=July 2007-->. Since these [phytochemicals often have [antiviral, [antibacterial, [antifungal and [antihelminthic properties, a plausible case can be made for self-medication by animals in the wild.

Some animals have digestive systems especially adapted to cope with certain plant toxins. For example, the koala can live on the leaves and shoots of the eucalyptus, a plant that is dangerous to most animals. {{cite web] of indigenous tribes, who then passed on safety information and cautions.

The use of herbs to treat disease is almost universal among non-industrialized societies. A number of traditions came to dominate the practice of herbal medicine at the end of the twentieth century:

Many of the pharmaceuticals currently available to physicians have a long history of use as herbal remedies, including opium, aspirin, digitalis, and quinine. The World Health Organization (WHO) estimates that 80 percent of the world's population presently uses herbal medicine for some aspect of primary health care. Herbal medicine is a major component in all traditional medicine systems, and a common element in Ayurvedic, homeopathic, naturopathic, traditional Chinese medicine, and Indigenous peoples of the Americas medicine.

According to the WHO, 74% of 119 modern plant-derived pharmaceutical medicines are used in ways that are similar to their traditional uses. Major pharmaceutical companies are currently conducting extensive research on plant materials gathered from the rainforests and other places for possible new pharmaceuticals. Introduction, Herbal Medicine, holisticonline.com

The use of, and search for, drugs and dietary supplements derived from plants have accelerated in recent years. Pharmacology, microbiology, botany, and natural-products chemists are combing the Earth for phytochemicals and leads that could be developed for treatment of various diseases. In fact, approximately 25% of modern drugs used in the United States have been derived from plants.







Herbs in history ]In the written record, the study of herbs dates back over 5,000 years to the Sumerians, who described well-established medicinal uses for such plants as laurel, caraway, and thyme. The first known Chinese herb book (or herbal), dating from about 2700 B.C., lists 365 medicinal plants and their uses - including ma-Huang, the shrub that introduced the drug ephedrine to modern medicine. The Egyptians of 1000 B.C. are known to have used garlic, opium, castor oil, coriander, mint, indigo, and other herbs for medicine and the Old Testament also mentions herb use and cultivation, including mandrake, vetch, caraway, wheat, barley, and rye.

Like their predecessors, the ancient Greeks and Romans made medicinal use of plants. Greek and Roman medicinal practices, as preserved in the writings of Hippocrates and - especially - Galen, provided the patterns for later western medicine. Hippocrates advocated the use of a few simple herbal drugs - along with fresh air, rest, and proper diet. Galen, on the other had, recommended large doses of more or less complicated drug mixtures - including plant, animal, and mineral ingredients. The Greek physician compiled the first European treatise on the properties and uses of medicinal plants, De Materia Medica. In the first century AD, Dioscorides wrote a compendium of more that 500 plants that remained an authoritative reference into the seventeenth century. Similarly important for herbalists and botanists of later centuries was the Greek book that founded the science of botany, Theophrastus’ Historia Plantarum, written in the fourth century B.C.

]The uses of plants for medicine and other purposes changed little during the Middle Ages. The early Christian church discouraged the formal practice of medicine, preferring faith healing; but many Greek and Roman writings on medicine, as on other subjects, were preserved by diligent hand copying of manuscripts in monasteries. The monasteries thus tended to become local centers of medical knowledge, and their herb gardens provided the raw materials for simple treatment of common disorders. At the same time, folk medicine in the home and village continues uninterrupted, supporting numerous wandering and settled herbalists. Among these were the “wise-women,” who prescribed herbal remedies often along with spells and enchantments. It was not until the later Middle Ages that women who were knowledgeable in herb lore became the targets of the witch hysteria. One of the most famous women in the herbal tradition was Hildegard of Bingen. A twelfth century Benedictine nun, she wrote a medical text called Causes and Cures.

]Medical schools began to return in the eleventh century, teaching Galen’s system. At the time, the Arabic world was more advanced in science than Europe. As a trading culture, the Arabs had access to plant material from distant places such as China and India. Herbals, medical texts and translations of the classics of antiquity filtered in from east to west.{{cite web] and The English Physician Enlarged (1653) by Nicholas Culpeper. Gerard’s text was basically a pirated translation of a book by the Belgian herbalist Dodoens and his illustrations came from a German botanical work. The original edition contained many errors due to faulty matching of the two parts. Culpeper’s blend of traditional medicine with astrology, magic, and folklore was ridiculed by the physicians of his day yet his book - like Gerard’s and other herbals - enjoyed phenomenal popularity. The Age of Exploration and the Columian Exchange introduced new medicinal plants to Europe. The Badianus Manuscript was an illustrated Aztec herbal translated into Latin in the 16th century.

But the seventeenth century also saw the beginning of a slow erosion of the pre-eminent position held by plants as sources of therapeutic effects. The introduction by the physician. Paracelsus of active chemical drugs (like arsenic, copper sulfate, iron, mercury, and sulfur), followed by the rapid development of chemistry and the other physical sciences in the eighteenth and nineteenth centuries, led increasingly to the dominance of chemotherapy - chemical medicine - as the orthodox system of the twentieth century.

Biological background All plants produce chemical Chemical compound as part of their normal metabolism activities. These include primary metabolites, such as sugars and fats, found in all plants, and secondary metabolites found in a smaller range of plants, some useful ones found only in a particular genus or species. Pigments harvest light, protect the organism from radiation and display colors to attract pollinators.

The functions of secondary metabolites are varied. For example, some secondary metabolites are toxins used to Plant defense against herbivory, and others are pheremones used to attract insects for pollination. Phytoalexins protect against bacterial and fungal attacks. Allelochemicals inhibit rival plants that are competing for soil and light.

Plants upregulate and downregulate their biochemical paths in response to the local mix of herbivores, pollinators and microorganisms. The chemical profile of a single plant may vary over time as it reacts to changing conditions. It is the secondary metabolites and pigments that can have therapeutic actions in humans and which can be refined to produce drugs.

Plants synthesize a bewildering variety of phytochemicals but most are derivatives of a few biochemical motifs.









The word drug itself comes from the Swedish language word "druug", which means 'dried plant'. Some examples are inulin from the roots of dahlias, quinine from the cinchona, morphine and codeine from the poppy, and digoxin from the digitalis.

The active ingredient in willow bark, once prescribed by Hippocrates, is salicin, or salicylic acid. The discovery of salicylic acid lead to the development of "aspirin", also known as "acetylsalicylic acid". "Aspirin" was originally a brand name, and is still a protected trademark in some countries. This medication was patented by Bayer AG.

Popularity A survey released in May 2004 by the National Center for Complementary and Alternative Medicine focused on who used :category:alternative medicine (CAM), what was used, and why it was used. The survey was limited to adults, aged 18 years and over during 2002, living in the United States.

According to this survey, herbal therapy, or use of natural products other than vitamins and minerals, was the most commonly used CAM therapy (18.9%) when all use of prayer was excluded. (See table 1 on page 8). More Than One-Third of U.S. Adults Use Complementary and Alternative Medicine Press release, May 27, 2004. National Center for Complementary and Alternative Medicine

Herbal remedies are very common in Europe. In Germany, herbal medications are dispensed by apothecaries (e.g., Apotheke). Prescription drugs are sold alongside essential oils, herbal extracts, or herbal teas. Herbal remedies are seen by some as a treatment to be preferred to chemical medications which have been industrially produced{{Fact|date=July 2007-->.

In the United Kingdom, the training of medical herbalists is done by state funded Universities. For example, Bachelor of Science degrees in herbal medicine are offered at Universities such as University of East London, Middlesex University, University of Central Lancashire, University of Westminster, University of Lincoln and Napier University in Edinburgh at the present.

Types of herbal medicine systems ’ Materia Medica, c. 1334 copy in Arabic, describes medicinal features of cumin and dill.Use of medicinal plants can be as informal as, for example, culinary use or consumption of an herbal tea or supplement, although the sale of some herbs considered dangerous is often restricted to the public. Sometimes such herbs are provided to professional herbalists by specialist companies. Many herbalists, both professional and amateur, often grow or "wildcrafting" their own herbs. Many common weeds have medicinal properties (e.g. dandelion).

In traditional Chinese medicine herbs (which may include animal and mineral parts) are divided into "Superior" (food grade), "Moderate" (to be taken for disease for a short time) and "Inferior" (toxic, short term) grades. Disease is attributed to imbalance between yin and yang energy. Yin and yang refer to polarities that may either support or undermine one another. An example would be rest and activity. Herbal formulas are based upon the organ system which is out of balance, with chief herbs addressing the main complaint, deputy herbs which reinforce the actions of the chief or address other affected organ systems, and servants which may harmonize, balance temperatures or tastes of the herbs, direct them to various parts of the body or assist penetration. Herbal formulas tend to have five to 15 herbs.

Some researchers trained in both western and Chinese medicine have attempted to deconstruct ancient medical texts in the light of modern science. One hypothesis that has emerged is that the yin-yang balance, at least with regard to herbs, corresponds to the pro-oxidant and anti-oxidant balance. This interpretation is supported by several investigations of the {ORAC ratings of various yin and yang herbs.

Eclectic medicine came out of the vitalist tradition, similar to physiomedicalism and bridged the European and Indigenous peoples of the Americas traditions. Cherokee medicine tends to divide herbs into foods, medicines and toxins and to use seven plants in the treatment of disease, which is defined with both spiritual and physiological aspects, according to Cherokee herbalist David Winston. Safety & Regulation--Who's Watching the Herbal Store?, Tillotson Institute of Natural Health

In India, Ayurvedic medicine has quite complex formulas with 30 or more ingredients, including a sizable number of ingredients that have undergone "alchemy", chosen to balance "Vata", "Pitta" or "Kapha."http://oneearthherbs.squarespace.com/language-of-herbs/

In addition there are more modern theories of herbal combination like William LeSassier's triune formula which combined Pythagoreanism with Chinese medicine ideas and resulted in 9 herb formulas which supplemented, drained or neutrally nourished the main organ systems affected and three associated systems. His system has been taught to thousands of influential American herbalists through his own apprenticeship programs during his lifetime, the William LeSassier Archive William LeSassier Archive website and the David Winston Center for Herbal Studies David Winston Center for Herbal Studies website

Routes of administration There are many forms in which herbs can be administered, these include:



The easiest route of administration which is common among indigenous healers is to chew the plant directly .

The roots of plants like echinacea, the fruit of the plant lycium (goji berry), the seeds of the emetic lobelia and the resins of myrrh have all been ingested directly as medicine.

Standardization and concentration can boost certain plant constituents while losing others.

Examples of plants used as medicine Few herbal remedies have conclusively demonstrated any positive effect on humans. Many of the studies cited refer to animal model investigations or in-vitro assays and therefore cannot provide more than weak supportive evidence..

 
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